What Are Some Common Types of Cross Coupling Reactions?
Several types of cross coupling reactions are widely utilized:
1. Suzuki-Miyaura Coupling: Involves the coupling of organoboronic acids with halides, using a palladium catalyst. 2. Heck Reaction: Couples alkenes with halides or triflates, typically utilizing palladium. 3. Stille Coupling: Employs organotin reagents to couple with halides. 4. Negishi Coupling: Uses organozinc reagents in the presence of a palladium or nickel catalyst. 5. Sonogashira Coupling: A copper and palladium-catalyzed coupling of terminal alkynes with halides.
