The essential elements involved in a cross coupling reaction include:
1. Catalyst: Most commonly a transition metal like palladium, nickel, or copper. 2. Ligands: These stabilize the catalyst and can influence its reactivity and selectivity. 3. Electrophilic Partner: Usually an organic halide or pseudo-halide. 4. Nucleophilic Partner: Often an organometallic reagent such as an organoboron, organozinc, or organotin compound.