Why is the Transcription Initiation Complex Important?
The transcription initiation complex is vital for the regulation of gene expression. It ensures that RNA polymerase II is accurately positioned and activated only when necessary. The complex also integrates various signals from the cell, enabling a coordinated response to different physiological conditions and environmental stimuli. Disruptions in the formation or function of the transcription initiation complex can lead to aberrant gene expression and are associated with various diseases, including cancer.
