Phosphoglycerate kinase (PGK) is an essential enzyme that plays a critical role in the glycolytic pathway, a central metabolic pathway for energy production in cells. It catalyzes the reversible transfer of a phosphate group from 1,3-bisphosphoglycerate to ADP, forming 3-phosphoglycerate and ATP. This reaction is one of the key steps in the generation of ATP, the primary energy currency of the cell.