How is Phosphoglycerate Kinase Studied in Research?
PGK is commonly studied using a variety of biochemical and biophysical techniques. X-ray crystallography and NMR spectroscopy are used to elucidate the enzyme's structure, while kinetic assays help in understanding its catalytic properties. Mutagenesis studies can identify key residues involved in substrate binding and catalysis, providing insights into the enzyme's mechanism of action.