E3 ubiquitin ligase is a crucial enzyme in the biological catalysis of ubiquitination, a process where ubiquitin proteins are attached to a substrate protein, marking it for various cellular processes, including proteasomal degradation, DNA repair, and cell signaling. E3 ligases are part of a larger ubiquitination system that includes E1 (ubiquitin-activating) and E2 (ubiquitin-conjugating) enzymes.
