Several factors can negatively impact catalytic processes:
1. Poisoning: Certain substances can bind irreversibly to the active sites of a catalyst, rendering it inactive. For example, sulfur compounds can poison metal catalysts. 2. Fouling: The accumulation of unwanted materials on the catalyst surface can block active sites. 3. Sintering: High temperatures can cause catalyst particles to agglomerate, reducing their surface area and activity. 4. Deactivation: Over time, catalysts can lose their activity due to physical or chemical changes.