What are the structural features of V-type ATPases?
V-type ATPases are complex enzymes composed of multiple subunits. The V1 domain typically contains eight different subunits (A-H) arranged in a hexameric ring structure, while the Vo domain includes six subunits (a, d, c, c', c", and e) forming a proton channel. The structural arrangement allows for efficient coupling of ATP hydrolysis with proton translocation, facilitating their role as molecular machines.
