What are the Physiological Implications of CETP Activity?
The activity of CETP has significant implications for cardiovascular health. By modulating the distribution of cholesterol esters and triglycerides among various lipoproteins, CETP influences the levels of HDL and LDL cholesterol. High CETP activity is often associated with lower levels of HDL cholesterol and higher levels of LDL cholesterol, thus increasing the risk of atherosclerosis and cardiovascular diseases.