Can CETP be Targeted for Therapeutic Interventions?
Given its role in lipid metabolism, CETP is a target for therapeutic interventions aimed at managing cholesterol levels. CETP inhibitors, such as anacetrapib and evacetrapib, have been developed to reduce CETP activity. By inhibiting CETP, these drugs aim to increase HDL cholesterol levels and decrease LDL cholesterol levels, potentially reducing the risk of cardiovascular diseases.