What are the Challenges in Catalytic Esterification and Acylation?
Despite their benefits, catalytic esterification and acylation face several challenges: 1. Catalyst Deactivation: Catalysts can lose their activity over time due to fouling, poisoning, or structural changes. 2. Selectivity Issues: Achieving high selectivity for the desired product can be challenging, especially in complex reaction mixtures. 3. Environmental Concerns: Some catalysts, especially strong acids and heavy metals, pose environmental and safety hazards.
