instrument sensitivity

What Are the Challenges in Achieving High Sensitivity?

Achieving high sensitivity in analytical instruments for catalysis research comes with several challenges:
1. Matrix Effects: The presence of complex reaction matrices can interfere with the detection of target analytes, reducing sensitivity.
2. Instrumental Noise: Background noise and interference can limit the sensitivity of analytical measurements.
3. Sample Stability: Some intermediates and products may be unstable or reactive, complicating their detection and quantification.
4. Cost and Complexity: Highly sensitive instruments are often expensive and require specialized training for operation and maintenance.

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