What are the Advantages of Palladium-Catalyzed Cross Coupling?
Palladium-catalyzed cross coupling reactions offer several significant advantages:
- High Selectivity: These reactions provide excellent selectivity, allowing for the formation of specific products without significant side reactions. - Functional Group Tolerance: The reactions can be performed in the presence of a variety of functional groups, making them versatile and broadly applicable. - Mild Reaction Conditions: Many palladium-catalyzed reactions can be conducted under relatively mild conditions, which is beneficial for sensitive substrates. - Scalability: These reactions are amenable to large-scale synthesis, making them suitable for industrial applications.