1. Sustainability: Microorganisms are renewable resources that can be cultivated in large quantities. 2. Specificity: Enzymes produced by microorganisms are highly specific, ensuring precise transformations and minimal by-products. 3. Mild Conditions: Reactions typically occur under mild conditions, reducing the need for extreme temperatures and pressures. 4. Versatility: A wide range of reactions can be catalyzed, from oxidation-reduction reactions to hydrolysis and synthesis.