Identifying no interaction can be achieved through several methods:
Kinetic Studies: Monitoring the reaction rate in the presence and absence of the catalyst can reveal if there is any catalytic effect. Spectroscopic Analysis: Techniques like NMR or IR spectroscopy can help identify whether the catalyst forms any intermediates with the reactants. Computational Modelling: Simulations can predict whether the catalyst is likely to interact with the reactants based on molecular dynamics.