Pore blockage can have several negative effects on catalytic processes: 1. Reduced Surface Area: The decrease in accessible surface area limits the number of active sites available for the reaction. 2. Increased Diffusional Resistance: Blocked pores hinder the diffusion of reactants to active sites and the removal of products, slowing down the overall reaction rate. 3. Deactivation: Prolonged blockage can lead to permanent deactivation of the catalyst, necessitating replacement or regeneration.