How Do Protic Solvents Affect Catalytic Reactions?
The impact of protic solvents on catalytic reactions can be multifaceted:
1. Stabilization of Intermediates: Protic solvents can stabilize charged intermediates through hydrogen bonding, making certain reaction pathways more favorable. 2. Solvent Polarity: The polarity of protic solvents can influence the solubility of the reactants and products, thereby affecting the overall reaction rate. 3. Proton Transfer: In reactions involving proton transfer, protic solvents can act as proton donors or acceptors, facilitating or accelerating the reaction.