There are several reasons to use in situ generation in catalysis:
Improved Reactivity: Reactive species generated in situ can be highly reactive and short-lived, making them more effective in driving the desired chemical transformations. Enhanced Selectivity: The localized generation of active species can help in achieving higher selectivity for the desired products by minimizing side reactions. Economic Benefits: In situ generation can reduce the need for expensive and often unstable pre-formed catalysts, lowering overall costs. Simplified Processes: The process can simplify reaction setups by eliminating the need to handle and store reactive intermediates separately.
