The importance of paraoxonase extends beyond its catalytic activity. These enzymes are linked to a variety of physiological functions and have been implicated in protecting against cardiovascular diseases, as they are associated with high-density lipoprotein (HDL) and help in preventing the oxidation of low-density lipoprotein (LDL). Additionally, paraoxonase enzymes have anti-inflammatory properties and are involved in the modulation of cellular oxidative stress, making them key players in maintaining cellular homeostasis.
