Understanding the mechanisms of catalytic reactions at the atomic level is crucial for designing more efficient catalysts. Conventional STM techniques are limited by their operational conditions, which do not accurately mimic the real-world environments in which industrial catalysts operate. HP-STM overcomes this limitation by allowing researchers to observe surface reactions and changes in real-time under high pressure. This ability to study surface interactions under realistic conditions provides invaluable insights into the behavior of catalysts, helping to optimize their performance.