Various types of catalysts can be used in the COPE reaction, including:
Transition Metal Catalysts: These include complexes of metals like manganese, iron, and tungsten, which are known for their high catalytic activity and selectivity. Organocatalysts: Organic molecules that can catalyze the reaction without the need for metals, often offering advantages in terms of sustainability and toxicity. Enzymatic Catalysts: Enzymes such as peroxidases that can catalyze the reaction under mild conditions, offering high specificity and environmental benefits.
