The CFTR protein functions as a channel for chloride ions and is regulated by cyclic AMP (cAMP)-dependent phosphorylation and ATP binding and hydrolysis. It belongs to the ATP-binding cassette (ABC) transporter family, which is involved in the transport of various molecules across cellular membranes. Mutations in the CFTR gene can disrupt its function, leading to the buildup of thick mucus in organs, particularly the lungs and pancreas.
