What Are the Limitations of CD Spectroscopy in Catalysis?
While CD spectroscopy is a powerful tool, it has some limitations:
Sensitivity: CD spectroscopy may not be sensitive enough to detect very small structural changes or low concentrations of chiral molecules. Complex Mixtures: Analyzing complex mixtures with multiple chiral components can be challenging due to overlapping CD signals. Solvent Effects: The choice of solvent can affect the CD spectra, complicating the interpretation of results.