Several factors contribute to site specificity in catalytic reactions:
1. Surface Structure: The atomic arrangement on the catalyst surface can create unique active sites. For example, surface defects, edges, and corners often provide distinct catalytic sites compared to flat terraces.
2. Electronic Properties: The electronic configuration of atoms at different sites affects their ability to interact with reactants. Variations in electronic properties can enhance or diminish catalytic activity at specific sites.
3. Adsorption Strength: The strength with which reactants adsorb onto different sites can vary, leading to preferential binding and reaction at certain locations.