1. Reaction Conditions: High temperature and pressure can accelerate the degradation of the catalyst support, leading to palladium leaching. 2. Catalyst Support: The nature of the support material affects the stability of palladium particles. Weak interactions between palladium and the support can result in metal loss. 3. Reagents and Solvents: Certain reagents and solvents can interact with palladium, forming soluble complexes that leach into the reaction medium. 4. pH Levels: Acidic or basic conditions can destabilize palladium species, increasing their solubility and resultant leaching.
