Given its role in protecting against oxidative damage, Mn SOD has significant therapeutic potential. Enhancing Mn SOD activity or expression could be beneficial in treating diseases associated with oxidative stress. For example, Mn SOD mimetics are being investigated as potential treatments for conditions such as ischemia-reperfusion injury, neurodegenerative diseases, and cancer. Furthermore, gene therapy approaches aim to increase Mn SOD expression in specific tissues to mitigate oxidative damage.
