Key principles of minimally invasive catalysis include: - Efficiency: Maximizing the performance of the catalyst to achieve high yields with minimal amounts. - Selectivity: Ensuring the catalyst directs the reaction towards the desired products, reducing by-products. - Sustainability: Using catalysts that are non-toxic, abundant, and can be easily recycled or regenerated. - Mild Conditions: Conducting reactions under mild temperatures and pressures to save energy and reduce equipment wear.