What are the Clinical Implications of Lipoprotein-Related Catalysis?
The catalytic processes involving lipoproteins have significant clinical implications. Dysregulation of these enzymatic activities can lead to lipid metabolism disorders, such as hyperlipidemia, atherosclerosis, and cardiovascular diseases. For example, deficiencies in LPL activity can result in elevated levels of triglycerides in the blood, increasing the risk of pancreatitis and cardiovascular events. Therapeutic strategies targeting these enzymes, such as LPL gene therapy or CETP inhibitors, are being explored to manage dyslipidemia and reduce cardiovascular risk.
