What Are the Challenges of Using SMS in Catalysis?
Despite its advantages, there are several challenges associated with using SMS in catalysis. One major challenge is the photobleaching of fluorescent probes, which can limit the duration of observations. Additionally, the attachment of fluorescent probes to molecules can sometimes alter their chemical properties and affect the catalytic process. Another challenge is the need for sophisticated instrumentation and data analysis techniques to accurately interpret the single-molecule data.
