While HTS offers many benefits, it also comes with challenges:
High costs: The equipment and reagents required for HTS can be expensive. Data management: The vast amount of data generated requires sophisticated data management systems. False positives/negatives: Ensuring the accuracy of results can be difficult, and there is always a risk of false positives or negatives. Complexity of reactions: Some catalytic reactions are too complex to be easily adapted to HTS methodologies.
