Despite their potential, the use of GEMs in catalysis is not without challenges and risks:
Regulatory Hurdles: The release of GEMs into the environment is subject to stringent regulatory oversight to prevent potential ecological impacts. Stability: Maintaining the stability and activity of engineered enzymes under industrial conditions can be challenging. Public Perception: There can be public resistance to the use of genetically modified organisms, which may impact the acceptance and adoption of GEM-based technologies.