What are the Challenges and Future Directions in PDT?
Despite its potential, PDT faces several challenges. One major issue is the limited penetration depth of light, which restricts its use to superficial or accessible tumors. Efforts are being made to develop new photosensitizers with absorption in the near-infrared region for deeper tissue penetration. Additionally, improving the selectivity and minimizing the side effects of photosensitizers remain critical areas of research. The integration of nanotechnology and the development of targeted delivery systems are promising approaches to overcome these challenges.
