What are the applications of MeDIP in catalysis research?
1. Gene Expression Regulation: By identifying methylation patterns in promoter regions of genes encoding catalytic enzymes, researchers can infer how DNA methylation affects gene expression and enzyme activity. 2. Epigenetic Modifications: MeDIP helps in studying how epigenetic modifications influence metabolic pathways and catalytic reactions, particularly in diseases where these pathways are disrupted. 3. Drug Development: Understanding methylation patterns can aid in the development of drugs targeting specific epigenetic markers, potentially altering the activity of enzymes involved in disease pathways. 4. Agricultural Biotechnology: MeDIP is used to study methylation in plants, providing insights into how epigenetic changes can affect enzyme activity related to plant growth and stress responses.