What Are the Applications of HDR in Biotechnology?
HDR has significant applications in biotechnology, particularly in the field of genome editing. Techniques such as CRISPR-Cas9 leverage HDR to introduce precise genetic modifications. By inducing a DSB at a specific locus and providing a homologous repair template, researchers can achieve targeted gene insertions, deletions, or corrections. This has profound implications for gene therapy, functional genomics, and the development of genetically modified organisms (GMOs).
