Base editing offers several advantages over traditional genome editing techniques. Firstly, it introduces fewer off-target effects due to the absence of double-strand breaks. Secondly, it allows for precise single-base modifications, which are critical for correcting point mutations that cause genetic diseases. Additionally, base editing is more efficient in certain contexts, as it does not rely on the cell's homology-directed repair (HDR) pathways, which are often inactive in non-dividing cells.
