Base editing relies heavily on catalytic mechanisms to achieve its precision. The process utilizes deaminase enzymes, which act as catalysts to convert cytosine (C) to uracil (U) or adenine (A) to inosine (I). These conversions are subsequently recognized and corrected by the cellular machinery, leading to a permanent base change. The catalytic activity of these enzymes is crucial for the specificity and efficiency of the editing process.
