What Are Some Challenges in Carbon-Carbon Coupling Reactions?
Despite their importance, carbon-carbon coupling reactions face several challenges: - Selectivity: Achieving high selectivity can be difficult, especially in complex molecules. - Reactivity: Some substrates may be less reactive and require more robust catalysts. - Scalability: Translating laboratory-scale reactions to industrial-scale can be challenging. - Cost: The use of precious metal catalysts like palladium can be expensive.