The Lineweaver-Burk plot, also known as a double-reciprocal plot, is a graphical representation of enzyme kinetics. This plot is commonly used to illustrate the catalytic activity of enzymes and to determine important kinetic parameters. By plotting the reciprocal of the reaction rate (1/v) against the reciprocal of the substrate concentration (1/[S]), researchers can derive a straight line whose intercepts and slope provide insights into the enzyme’s catalytic properties.