What Are Histone Deacetylases (HDACs) and Their Function?
Histone deacetylases are enzymes that remove acetyl groups from lysine residues on histones, counteracting the activity of HATs. By deacetylating histones, HDACs promote chromatin condensation, thus repressing gene transcription. There are several classes of HDACs, classified based on their structure and function. HDAC inhibitors are being explored as therapeutic agents for various diseases, including cancer, due to their ability to alter gene expression patterns.
