How Can Histone Acetylation be Studied Experimentally?
Histone acetylation can be studied using various experimental techniques. Chromatin immunoprecipitation (ChIP) assays can identify specific acetylation sites and associated proteins. Mass spectrometry offers detailed insights into the acetylation status of histones. Additionally, enzyme assays can measure the activity of HATs and HDACs. These methods help elucidate the dynamic and reversible nature of histone acetylation.
