1. Advanced Reactor Design: Employing advanced reactor designs like microreactors or fluidized bed reactors can improve heat and mass transfer. 2. Catalyst Optimization: Developing more robust catalysts that resist deactivation and can be regenerated easily. 3. Modeling and Simulation: Using computational tools to model and simulate the scale-up process can help predict and mitigate potential issues. 4. Pilot Plants: Running pilot plant studies to gather data and refine the process before full-scale production. 5. Process Intensification: Techniques such as process intensification can enhance the efficiency and sustainability of catalytic processes.