Identifying inadequate equilibration involves monitoring the reaction over time and analyzing the reaction products. Key indicators include:
Time-Dependent Yield: If the yield of the desired product does not stabilize over time, it is a sign that equilibrium has not been reached. By-Product Formation: A high concentration of by-products may indicate that the reaction pathway is not optimized, suggesting inadequate equilibration. Inconsistent Kinetic Data: Variability in kinetic parameters can be a strong indicator of inadequate equilibration.
