OAT is regulated at multiple levels, including gene expression, post-translational modifications, and feedback inhibition. The expression of the OAT gene can be influenced by factors such as diet, hormonal changes, and stress. Post-translational modifications, such as phosphorylation, can alter the enzyme's activity. Additionally, the enzyme is subject to feedback inhibition by its products, ensuring that the reaction does not proceed unchecked and disrupt cellular homeostasis.