High affinity can be achieved through several strategies:
Active Site Design: Tailoring the active sites of the catalyst to match the electronic and structural properties of the substrate can significantly enhance affinity. Surface Modifications: Chemical modifications of the catalyst surface can improve substrate binding and orientation, leading to higher affinity. Nanostructuring: Creating nanostructured catalysts increases the surface area and provides more active sites, which can enhance substrate interactions. Ligand Engineering: Designing specific ligands that can form strong bonds with the substrate can improve the overall affinity of the catalytic system.