CSA is typically measured using NMR spectroscopy. In liquid-state NMR, CSA effects are often averaged out due to rapid molecular tumbling. However, in solid-state NMR, CSA becomes more pronounced. Techniques such as Magic Angle Spinning (MAS) can be employed to partially average out CSA, allowing for better resolution of the spectra. Additionally, 2D NMR techniques can be used to separate CSA from other interactions, providing a clearer understanding of the anisotropic properties of the sample.
