hydroboration oxidation

How does the Mechanism Work?

The hydroboration step involves the syn-addition of the borane to the alkene, forming a trialkylborane intermediate. This step is typically facilitated by a catalyst to enhance the rate and selectivity of the reaction. The oxidation step involves the conversion of the trialkylborane to the alcohol using hydrogen peroxide (H2O2) in the presence of a base such as sodium hydroxide (NaOH). The overall mechanism can be summarized as follows:
1. Hydroboration: R-CH=CH2 + BH3 → R-CH2-CH2-BH2
2. Oxidation: R-CH2-CH2-BH2 + H2O2 + NaOH → R-CH2-CH2-OH + NaBO2

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