What are the Advantages of Catalytic Hydroboration-Oxidation?
- Regioselectivity: The reaction selectively produces anti-Markovnikov alcohols, which are often difficult to synthesize using other methods. - Stereospecificity: The syn-addition of borane ensures that the resulting alcohol retains the stereochemistry of the starting alkene. - Mild Conditions: The reaction proceeds under relatively mild conditions, reducing the risk of side reactions and degradation of sensitive functional groups. - Scalability: Catalytic hydroboration-oxidation is scalable and can be applied to industrial processes for the synthesis of fine chemicals, pharmaceuticals, and agrochemicals.
