steric effects

How Do Steric Effects Impact Selectivity?

Selectivity in catalysis often hinges on steric effects. Catalysts with specific spatial configurations can favor the formation of one product over another by blocking certain pathways or orientations. For example, in asymmetric catalysis, chiral catalysts utilize steric effects to produce one enantiomer preferentially. This is crucial in the pharmaceutical industry, where the chirality of a molecule can significantly impact its biological activity.

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