How do Ring Strain and Ring Size Influence Catalytic Reactions?
The strain in ring structures can significantly influence their reactivity. Smaller rings, such as three-membered [epoxides]() or [cyclopropanes](), have higher ring strain, making them more reactive. This increased reactivity can be advantageous in catalytic processes where these strained rings can be opened to form new bonds. Conversely, larger rings like [macrocycles]() have less ring strain but offer multiple binding sites, which can be beneficial in complex catalytic transformations.
