How Do Peptidyl Mimetics Enhance Catalytic Activity?
Peptidyl mimetics enhance catalytic activity by providing a scaffold that can precisely position functional groups in a three-dimensional space. This precise positioning is crucial for effective catalytic mechanisms such as nucleophilic attack, proton transfer, or metal coordination. The stability of peptidyl mimetics also allows them to operate under harsh conditions where natural peptides might degrade, thus expanding the range of possible catalytic applications.
